Radiation plus immunotherapy for liver cancer with major vein clot
Treatments studied
Part of Cancer clinical trials.
This trial tests adding radiation (SBRT) to a combination of immunotherapy drugs (atezolizumab and bevacizumab) for people with liver cancer that has spread into the main portal vein. It aims to see if this approach can shrink tumors and improve outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older.
- You have liver cancer (HCC) with a tumor clot in the main portal vein or its first branch.
- Your cancer did not get worse after 2 cycles of atezolizumab plus bevacizumab.
- You have up to 5 tumors in the liver, and the tumor clot is only in the liver.
- Your liver function is good (Child-Pugh A) and your blood counts are adequate.
- You have no active bleeding or untreated varices in your stomach or esophagus.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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