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NCT06824025Possibly a fitRecruiting

Comparing two drugs for headache after spinal anesthesia in C-section

Post-Dural Puncture Headache

Part of Brain & nervous system clinical trials.

This trial tests if a combination of neostigmine and atropine works better than lidocaine for treating severe headaches that can happen after spinal anesthesia during a planned C-section. It aims to find a more effective way to relieve this type of headache.

Summary written for real people, not researchers, by Clin2.

Phase
Early Phase 1
Enrollment
111 people
Ages
18 years to 35 years
Study type
Interventional

Who can take part

  • You are a woman who recently had a planned C-section under spinal anesthesia (not emergency).
  • You are between 18 and 35 years old.
  • You have a postpartum headache that your doctor rates as at least a 4 on a 0–10 pain scale and scores 2 or higher on the Lybecker headache scale.
  • You do not have high blood pressure caused by pregnancy (preeclampsia).
  • You do not have asthma or a history of asthma, migraines, or trigeminal neuralgia (a nerve pain condition).
  • You did not have heavy bleeding after delivery or need general anesthesia or a failed spinal block.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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