Comparing two maintenance drugs for ovarian cancer without DNA repair defects
Part of Cancer, Hormones & metabolism, Women’s health & pregnancy clinical trials.
This study compares two maintenance drugs (niraparib vs. bevacizumab) for people with advanced ovarian cancer who do not have certain DNA repair issues (BRCA mutation or HRD). It aims to see which drug works better to keep cancer from coming back.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have been diagnosed with advanced ovarian cancer (stage III or IV) and have had chemotherapy.
- Your cancer should not have a BRCA gene mutation or a positive HRD test (these are DNA repair problems).
- If you had surgery, it must have been after chemotherapy (not as the first treatment).
- You should have already been taking either bevacizumab or niraparib as maintenance therapy after chemotherapy.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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