RMTT chemo for newly diagnosed PCNS lymphoma
Part of Blood & lymphatic, Brain & nervous system, Cancer clinical trials.
This trial tests a combination of four chemotherapy drugs (Rituximab, Methotrexate, Temozolomide, and Thiotepa) as the first treatment for people newly diagnosed with primary central nervous system diffuse large B-cell lymphoma. It aims to see if this regimen is safe and effective for patients who have not had any prior systemic therapy.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have been diagnosed with a new, untreated primary brain lymphoma (DLBCL type) that has at least one measurable tumor (1.5 cm or larger across).
- You have not received any previous cancer treatment (except steroids to control symptoms).
- You are in generally stable health (ECOG performance status 0-3, meaning you can carry out daily activities with little to no help).
- If you could become pregnant, you agree to use effective birth control during the study and for 6 months after, and you are not pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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