Bleeding patterns in teens with Turner syndrome on progesterone
Treatments studied
Part of Genetic & congenital, Heart & circulation, Hormones & metabolism, Kidney & urinary, Women’s health & pregnancy clinical trials.
This study looks at how different ways of taking progesterone (a hormone given along with estrogen) affect bleeding patterns in teens with Turner syndrome. The goal is to find the best hormone schedule to cause regular, predictable periods.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with Turner syndrome and have primary ovarian insufficiency (your ovaries do not produce enough hormones naturally).
- You are already taking estrogen replacement therapy at an adult dose—either a skin patch (50-200 mcg daily) or an oral pill (2–4 mg daily).
- You have already had your first period (menarche).
- You are not sexually active and do not need birth control, or you use a method other than an IUD, arm implant, or Depo-Provera shot.
- You speak English or Spanish.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial compares oral and transdermal (patch) estrogen to find the right dose for women with Turner syndrome. It aims to see which method works best for hormone replacement.
This trial compares different hormone treatments to help start puberty in girls and young women with Turner syndrome who have not yet begun puberty. It aims to find the best approach to promote breast development and uterus growth.
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This study compares two ways to give progesterone to young people on estrogen replacement therapy to see how they affect the lining of the uterus. It will help find which approach may be safer and more effective for your health.
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