Clin2
NCT06837831Possibly a fitRecruiting

Mepilex Lite Dressing for radiation skin damage on anal area

Rectal Cancer, RadiotherapyAnal PainAcute Radiation DermatitisAnal Canal

Treatments studied

Part of Cancer, Digestive system clinical trials.

This trial tests a special wound dressing (Mepilex Lite) to treat skin burns from radiation therapy in patients with rectal cancer. It may help heal the skin around the anal canal more comfortably.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
274 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have been diagnosed with rectal cancer
  • Your doctor has recommended radiation therapy
  • This is your first time receiving radiation and you have developed grade 2 or higher skin irritation (redness, swelling, peeling) in the anal area
  • You are 18 years old or older
  • You do not have severe allergies to wound dressing materials
  • You are able to complete the full radiation treatment without stopping early

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07065175Not yet recruiting· Phase 2
Liquid dressing for chronic radiation rectal injury

This study tests a liquid dressing that is applied to the rectum to help heal damage caused by radiation therapy. It may reduce bleeding, pain, and other symptoms of chronic radiation proctitis.

Beijing, Beijing Municipality
NCT07154316Recruiting· Phase 2
Short radiation plus drugs for MSS rectal cancer

This trial tests a shorter course of radiation therapy followed by a combination of chemotherapy, immunotherapy, and a pain-relief medication, compared to the standard approach. It is for people with a certain type of rectal cancer that has not spread.

Fuzhou, Fujian
NCT07729423Recruiting
Mepitel Film for skin protection during breast radiation

This trial tests if a special film placed on the skin can reduce radiation side effects in people who have had breast cancer surgery and are now getting radiation therapy.

Singapore
NCT07548736Not yet recruiting· Phase 2
Dexamethasone enema for rectal irritation after radiation therapy

This study tests whether giving a steroid medication (dexamethasone) as an enema can help reduce the side effect of radiation treatment on the rectal area. If you are getting radiation for rectal cancer and are bothered by rectal irritation, this might be a helpful addition to your care.

Guangzhou, Guangdong
NCT07068763Recruiting· Phase 2
Short radiation plus drugs for early rectal cancer

This trial tests a combination of short-course radiation, chemotherapy (capecitabine), and two immunotherapy drugs (PD-1 and CTLA-4 inhibitors) for people with early-stage rectal cancer who want to avoid surgery and keep their anus. The goal is to see if this treatment can shrink the tumor enough to avoid major surgery.

Hangzhou, Zhejiang
NCT05972655Recruiting· Phase 2
Testing shorter rectal radiation with chemotherapy plus immunotherapy

This Phase 2 study tests whether a shorter course of radiation, combined with chemotherapy (CAPOX) and an immunotherapy drug (tislelizumab), can control middle and low rectal cancer. It may also help people who strongly want to keep their anus, if the cancer and overall health fit the study rules.

Hanzhou, Zhejiang

Hear when a new Rectal Cancer, Radiotherapy trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.