Dexamethasone enema for radiation damage to the rectum
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial tests whether a steroid enema (dexamethasone) can help prevent or reduce bowel damage caused by radiation therapy for rectal cancer. If you're starting or recently started radiation for rectal cancer, this may help protect your bowel health.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old
- You have been diagnosed with rectal cancer (confirmed by biopsy)
- You are receiving standard pelvic radiation therapy (40-50.4 Gy over 25-28 treatments)
- You are in good enough health to tolerate treatment (ECOG score 0-1)
- You have not received pelvic radiation before
- You are not pregnant, breastfeeding, or planning major surgery during the study
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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