Dexamethasone enema for rectal irritation after radiation therapy
Treatments studied
Part of Cancer, Digestive system clinical trials.
This study tests whether giving a steroid medication (dexamethasone) as an enema can help reduce the side effect of radiation treatment on the rectal area. If you are getting radiation for rectal cancer and are bothered by rectal irritation, this might be a helpful addition to your care.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have been diagnosed with rectal cancer.
- You are currently receiving standard radiation therapy to the pelvic area (a total dose of 40–50.4 Gy over 25–28 sessions).
- You have not had radiation therapy to the pelvic area before.
- Your overall health is reasonably good (able to care for yourself and expected to live more than 6 months).
- You are not allergic to dexamethasone and are able to receive an enema.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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