Clin2
NCT06848465Worth exploringRecruiting

Radiation plus chemo-immunotherapy for colon cancer with liver spread

Colorectal CancerLiver MetastasisLDRT

Treatments studied

Part of Cancer, Digestive system clinical trials.

This trial tests a combination of low-dose radiation, chemotherapy, and immunotherapy for people with colorectal cancer that has spread only to the liver. The goal is to see if this approach can shrink tumors and improve outcomes.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
9 people
Ages
18 years to 80 years
Study type
Interventional

Who can take part

  • You must be between 18 and 75 years old.
  • You must have a type of colon or rectal cancer called MSS or pMMR adenocarcinoma (these are specific genetic features).
  • The rectal cancer must be at a certain stage (T3–4 or N1–2) and have spread to the liver but nowhere else.
  • You cannot have had any previous cancer treatment like chemotherapy, radiation, or immunotherapy.
  • You need to be in generally good health, able to care for yourself (ECOG score 0 or 1), and have adequate heart, liver, kidney, and blood function.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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