Clin2
NCT05359393Possibly a fitNot yet recruiting

Immunotherapy combination for rectal cancer with liver or lung spread

Advanced Rectal CancerLiver MetastasisPulmonary MetastasisMicrosatellite Stable Colorectal Carcinoma

Part of Cancer, Digestive system, Immune system & allergy, Lungs & breathing clinical trials.

This trial tests a combination therapy that includes an immunotherapy drug (called anti-PD-1) for people with rectal cancer that has spread to the liver or lungs. The goal is to see if this treatment can help shrink or control the cancer, and it may be an option if you haven't had treatment yet.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
52 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • Be between 18 and 75 years old
  • Have rectal cancer that has spread to your liver or lungs (but not other organs)
  • Not have received treatment for this cancer before
  • Have a specific type of rectal cancer called 'adenocarcinoma' that is located less than 10 cm from the anus
  • Have good overall health (as measured by a performance score) and adequate organ function
  • Have a stable type of cancer (called MSS) with known genetic markers

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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