Pre-surgery calming medicine for children ages 1 to 6
Treatments studied
Part of Pain clinical trials.
This study tests a combination of two medicines (dexmedetomidine and esketamine) given as a nasal spray to help children relax before surgery. The goal is to find the best dose that works well with the least side effects.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your child is between 1 and 6 years old
- Your child is scheduled for surgery that requires general anesthesia
- Your child is in good health (classified as ASA I or II)
- Your child’s weight is normal for their age
- You are willing to sign a consent form
- Your child has not had a cold or upper respiratory infection in the last 2 weeks
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study tests a skin patch that helps children relax before surgery. The patch contains a medicine that is absorbed through the skin to reduce anxiety, so the child may need less anesthesia.
This trial compares two safe, common ways to help children relax before surgery: a medicine sprayed in the nose versus a medicine given by mouth. The goal is to see which one works better and is easier for kids.
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This trial tests a nasal spray sedative (dexmedetomidine) given before surgery to see if it's safe when there's less monitoring. It may help people who need general, spinal, or nerve block anesthesia feel calm and comfortable.
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