Treatment
Dexmedetomidine clinical trials
We’re tracking 190 recruiting studies that include Dexmedetomidine, each written for real people, not researchers, below.
Recruiting studies
- NCT07522736Recruiting
Spinal anesthesia with dexmedetomidine for knee surgery
This trial tests adding dexmedetomidine (a calming medication) to bupivacaine (numbing medication) injected into the spine during knee surgery. The goal is to improve pain relief and recovery after surgery.
CairoAges 18–65 - NCT06399185RecruitingPhase 4
Medicines for catheter discomfort after bladder or prostate surgery
This study tests whether two medicines, dexmedetomidine and esketamine, can reduce discomfort from a urinary catheter after bladder or prostate surgery. If you are having this type of surgery and need a catheter, this trial may help find a better way to manage that discomfort.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07329933Recruiting
Steroids and sedatives for faster recovery after gallbladder surgery
This trial tests if adding two medicines, dexamethasone and dexmedetomidine, helps the stomach and intestines work better after keyhole gallbladder removal. The goal is to see if the combination can get your digestion back to normal faster.
BanhāAges 18–65 - NCT06981494Recruiting
Study of two medicines for relaxing blood pressure during ear and nose surgery
This trial tests if adding a second medicine, ketamine, to dexmedetomidine helps control blood pressure better during ear or nose surgery. It may lead to safer and smoother anesthesia for patients needing controlled low blood pressure.
SohagAges 18–60 - NCT05821972RecruitingPhase 4
Breathing-mist medicines for cleft palate surgery pain control
This trial tests whether a breathing mist of two medicines (dexmedetomidine plus ketamine) works better than dexmedetomidine alone during cleft palate repair surgery. It may help improve comfort and safety around anesthesia for eligible patients.
AsyutAges 1–4 - NCT06614010RecruitingPhase 1
Testing drugs for hip replacement recovery
This trial studies how giving a sedative drug (dexmedetomidine) through different routes, combined with a numbing shot for the hip, can help reduce confusion and agitation right after hip replacement surgery. The goal is to find which method works best for a smoother wake-up.
Jinan, ShandongAges 18–65 - NCT06837844Recruiting
Pain relief study for knee replacement surgery
This trial tests a combination of two pain-relief methods after total knee replacement: a spinal injection and a nerve block in the thigh. It aims to provide better pain control during and after surgery.
Kafr ash Shaykh, KafrelsheikhAges 18–75 - NCT07308756RecruitingPhase 4
Study on two drugs for better recovery after surgery
This trial tests if giving two medicines, dexmedetomidine and esketamine, during and after surgery can help you feel better and recover more comfortably. It is for adults having general anesthesia for at least one hour who will use a patient-controlled pain pump afterward.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07369128RecruitingPhase 4
Comparing two sleep medicines for children having an MRI
This trial tests whether using one sleep medicine (propofol) alone works as well as using it with another medicine (dexmedetomidine) for children getting an MRI. The goal is to find the safest and most effective way to help kids stay still during the scan.
Boston, MassachusettsAges 1–12 - NCT07777627Recruiting
Comparing two spinal pain relievers after lumbar spine surgery
This trial compares two different medications (morphine and dexmedetomidine) given through a spinal injection to see which provides better pain relief after lumbar spine surgery. If you qualify, you will receive one of these treatments or a placebo to help manage your pain after the operation.
Tanta, El-GharbiaAges 21–60 - NCT07780760Recruiting
Numbing throat spray to ease pain after tonsil removal in children
This study tests whether a numbing mist sprayed into the throat before surgery can reduce sore throat pain children feel after having their tonsils removed. It compares two numbing medicines to see if one works better than the other.
Al FayyumAges 3–15 - NCT07506044Recruiting
Dexmedetomidine in epidural for labor pain relief
This trial tests adding dexmedetomidine to the epidural medicine used for pain relief during labor. If you are in early labor with a healthy pregnancy, this could help manage pain more effectively.
Shebeen El KomAges 18–40 - NCT06082856Recruiting
Dexmedetomidine for heart stability during outpatient surgery
This trial tests whether a drug called dexmedetomidine, given during general anesthesia, helps keep your heart rate and blood pressure stable during outpatient surgery. It may be an option if you are having a minor surgery and are not on certain heart medications.
NîmesAges 18 years+ - NCT07066605Recruiting
Dexmedetomidine for agitation during breathing tube removal
This trial tests whether a sedative called dexmedetomidine can reduce agitation in ICU patients when they are being weaned off a breathing tube. If you experience restlessness or agitation during the weaning process, this medication might help you stay calm.
SohagAges 19 years+ - NCT06498700Enrolling by invitation
Preventing PTSD After Brain Surgery: Ketamine vs Dexmedetomidine
This study tests whether giving a low dose of ketamine or dexmedetomidine during brain surgery can help prevent post-traumatic stress disorder (PTSD) afterward. Both medicines are safe and used to manage pain and anxiety.
Zagazig, Sharqia ProvinceAges 18–60 - NCT06030804Recruiting
Dexmedetomidine during surgery and long-term survival
This trial studies whether adding a medication called dexmedetomidine during cancer surgery can improve long-term survival. It is for older adults having major cancer surgery that lasts at least two hours and who will need a pain pump after the operation.
Hefei, AnhuiAges 60 years+ - NCT05640453RecruitingPhase 4
Testing pregabalin or dexmedetomidine for post-surgery delirium
This study compares two medicines—pregabalin and dexmedetomidine—to treat confusion (called delirium) after heart bypass surgery. It aims to see which drug works better to reduce delirium symptoms in older adults after coronary artery bypass surgery.
Tanta, El-Gharbia GovernorateAges 65 years+ - NCT07170267Recruiting
Pain relief study for cesarean section
This study tests whether a nerve block in the lower belly wall (transversalis fascia plane block) or a medication injected into the spinal fluid (intrathecal dexmedetomidine) provides better pain relief for mothers having a planned cesarean section under spinal anesthesia.
Tanta, El-GharbiaAges 18–40 - NCT07078201RecruitingPhase 4
Comparing two pain meds in spinal anesthesia for leg surgery
This study compares two medicines (dexmedetomidine and fentanyl) added to a spinal numbing shot for people having planned leg or knee surgery. The goal is to see which one works better to keep your blood pressure stable, and to make the numbing last while keeping you comfortable.
Port SaidAges 20–60 - NCT07675616Recruiting
Comparing two drugs for numbing the eye before tear-duct surgery
This trial tests whether adding dexmedetomidine or magnesium sulfate to lidocaine makes numbing the eye more effective for tear-duct surgery. The goal is to find which combination provides better pain control during surgery.
CairoAges 18 years+ - NCT07693621Recruiting
Pain relief medicine added to numbing drug for gallbladder surgery
This trial tests if adding dexmedetomidine or magnesium to a standard numbing medication (bupivacaine) injected into the belly during gallbladder surgery can improve pain control and recovery. It aims to find a better way to manage pain after surgery.
AlexandriaAges 18–60 - NCT07343843Recruiting
Virtual reality vs sedative for anxiety during C-section
This study compares two ways to reduce anxiety and stress during a planned C-section: using a virtual reality headset versus a sedative medicine given through an IV. It aims to see which approach helps mothers feel calmer and supports better outcomes for both mom and baby.
Banhā, BenhaAges 18 years+ - NCT06575179RecruitingPhase 4
Testing a sedative to reduce anesthesia needs during gallbladder surgery
This trial tests if a sedative called dexmedetomidine can lower the amount of anesthetic (sevoflurane) needed to block body responses during keyhole gallbladder surgery. If it works, it may make anesthesia safer for patients.
Fuzhou, FujianAges 18–45 - NCT06853431RecruitingPhase 4
Pre-surgery calming medicine for children ages 1 to 6
This study tests a combination of two medicines (dexmedetomidine and esketamine) given as a nasal spray to help children relax before surgery. The goal is to find the best dose that works well with the least side effects.
Wenzhou, ZhejiangAges 1–6
What Dexmedetomidine is being studied for
Conditions with recruiting Dexmedetomidine studies.
Common questions
- Are there clinical trials studying Dexmedetomidine?
- Yes. Clin2 currently lists 190 recruiting studies that include Dexmedetomidine, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Dexmedetomidine trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Dexmedetomidine an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Dexmedetomidine or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.