Semaglutide for obesity with different insulin resistance levels
Part of Hormones & metabolism clinical trials.
This study tests whether semaglutide (a weight-loss medication) works differently in people with varying degrees of insulin resistance (how well your body uses sugar). If you are obese without diabetes, you may be able to join.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Aged 18 to 60 years
- Body mass index (BMI) between 30 and 40
- If BMI is 30–35, you need a weight-related health condition like high blood pressure or abnormal cholesterol
- No diabetes (type 1 or type 2) and not taking diabetes medicines
- No recent use of GLP-1 drugs (like Ozempic) or other weight-loss medications
- No major weight changes (more than 5% up or down) in the last 3 months
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether semaglutide (a medicine that helps control blood sugar and weight) can improve outcomes for people with type 1 diabetes who have a higher body weight. It may help if you have had type 1 diabetes for at least 3 years and have a BMI of 30 or more, or 27 or more with a related health problem.
This trial tests if semaglutide, a medicine used for diabetes and weight loss, can help people with both psoriasis and obesity. You may qualify if you have moderate to severe psoriasis, a high body weight, and are of Chinese descent.
This study tests a medication called semaglutide (which helps with weight loss) in people with obesity who have struggled to lose weight before. It will see how much weight participants can lose while taking the drug.
This study tests if a medication called semaglutide can help people with obesity lose weight by changing the bacteria in their gut. You may be able to join if you have obesity, have tried to lose weight before, and are generally healthy.
This study tests an injectable medication called semaglutide to help with weight loss in people with a BMI of 28 or higher who have struggled to lose weight before. It compares the study drug to a similar approved weight loss medicine (Wegovy).
This study tracks how semaglutide (an injectable medication that reduces appetite) helps adults lose weight in everyday life. Researchers want to understand how well it works and how safe it is for people starting the treatment.
Hear when a new Obesity and Obesity-related Medical Conditions trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.