Clin2
NCT06863272Possibly a fitRecruiting

Study of ifinatamab deruxtecan for advanced prostate cancer

Castration-Resistant Prostatic CancerMetastasis

Treatments studied

Part of Cancer, Kidney & urinary clinical trials.

This trial tests a new drug, ifinatamab deruxtecan, either alone or in combination with other treatments, for men with metastatic castrate-resistant prostate cancer that has worsened despite hormone therapy. It aims to see if this approach can help shrink or slow the cancer.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
360 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must have prostate cancer that has spread to other parts of the body and is still growing despite hormone therapy.
  • You must have tried and not responded well to one or two types of anti-androgen therapy (like enzalutamide or abiraterone).
  • You cannot have had chemotherapy with a taxane drug for your prostate cancer.
  • You must have a good performance status (able to care for yourself and up and about at least half the day).
  • You cannot have a history of lung problems like interstitial lung disease or pneumonitis that needed treatment with steroids.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06330064Recruiting· Phase 1/Phase 2
Study of a new drug for advanced solid tumors

This study tests a new drug called Ifinatamab Deruxtecan (I-DXd) for people with several types of advanced cancer that has grown despite standard treatments. The drug is designed to target and attack cancer cells directly, potentially shrinking tumors or slowing their growth.

Los Angeles, California
NCT07287150Recruiting· Phase 2
Testing Inavolisib for advanced prostate cancer

This study tests a new targeted therapy called inavolisib for men with advanced, hormone-resistant prostate cancer that has spread. The drug may work by blocking a specific pathway that helps cancer grow. Participants must have already tried one second-generation hormone therapy and have a tumor sample available for testing.

Los Angeles, California
NCT07590934Recruiting· Phase 1/Phase 2
Drug combination study for advanced prostate cancer

This study tests several new drug combinations for men with advanced prostate cancer that has spread and stopped responding to standard hormone treatments. It aims to find better ways to control the disease and improve outcomes.

Duarte, California
NCT07630974Recruiting· Phase 1/Phase 2
New Cancer Drug for Children With Hard-to-Treat Solid Tumors

This trial tests a new drug called ifinatamab deruxtecan in children whose solid tumors (cancers that form lumps, excluding brain tumors) have come back or stopped responding to previous treatments. The drug is designed to target and kill cancer cells while potentially causing fewer side effects than standard chemotherapy.

Los Angeles, California
NCT06492122Recruiting· Phase 1
Study of a radioactive drug for advanced prostate cancer

This trial tests a new radioactive treatment, [225Ac]Ac-FL-020, for men with metastatic castration-resistant prostate cancer (mCRPC) that has gotten worse despite other treatments. It's for those who have had at least one prior hormone therapy or chemotherapy.

Duarte, California
NCT06925737Recruiting· Phase 3
Study of I-DXd for metastatic prostate cancer

This study tests a new drug called Ifinatamab Deruxtecan (I-DXd) for people with metastatic prostate cancer that has stopped responding to hormone therapy. It may help by targeting and destroying cancer cells in a different way.

Phoenix, Arizona

Hear when a new Castration Resistant Prostatic Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.