Clin2
NCT06863831Possibly a fitEnrolling by invitation

Comparing YSQTG to placebo with standard treatment for esophageal cancer

Esophageal Squamous Cell Carcinoma (ESCC)

Part of Cancer, Digestive system clinical trials.

This trial tests whether adding an herbal granule (YSQTG) to standard chemotherapy with or without immunotherapy helps patients with a specific type of advanced esophageal cancer. It focuses on people whose cancer is stage III to IVa and who have not had treatment yet.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
536 people
Ages
18 years to 80 years
Study type
Interventional

Who can take part

  • You have squamous cell esophageal cancer that is stage III to IVa and can be removed with surgery.
  • You have not had any previous treatment for this cancer.
  • You are between 18 and 80 years old.
  • You have a Karnofsky score of 70 or higher (able to care for most daily needs).
  • You have symptoms that match a particular traditional Chinese medicine pattern called 'kidney deficiency with blood stasis and toxin stagnation'.
  • You do not have other serious illnesses, other cancers, or allergies to the study drugs.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07463573Recruiting· Phase 3
New drug vs chemotherapy for advanced esophageal cancer

This trial tests a new drug, QLC5508, against standard chemotherapy for people with advanced esophageal cancer that has already been treated. It aims to see if the new drug works better.

Beijing, Beijing Municipality
NCT07751055Recruiting· Phase 2
Chemotherapy and radiation with immunotherapy before surgery for esophageal cancer

This trial tests whether adding two immunotherapy drugs to standard chemotherapy and radiation before surgery can help shrink esophageal cancer and improve outcomes. It is for people with a certain type of esophageal cancer that can be removed with surgery.

Guangzhou, Guangdong
NCT07317609Recruiting· Phase 1
Immunotherapy plus chemo before endoscopic resection for esophageal cancer

This trial tests a treatment plan that combines immunotherapy with chemotherapy before possible endoscopic surgery. It is for people with a specific type of esophageal cancer that has not been treated before and is either potentially removable or not suitable for standard surgery.

Shanghai, Shanghai Municipality
NCT07678580Not yet recruiting· Phase 2
Radiation plus immunotherapy and chemo before surgery for esophageal cancer

This trial tests a combination of short-course radiation, an immunotherapy drug called tislelizumab, and chemotherapy before surgery for esophageal cancer that has spread to nearby lymph nodes but hasn't spread to distant organs. The goal is to shrink the tumor before surgery and improve outcomes.

Xi'an, Shaanxi
NCT07390565Enrolling by invitation
Study of YSQTG with immunotherapy and chemo for advanced lung cancer

This trial tests a Chinese herbal formula (YSQTG) combined with standard immunotherapy and chemotherapy for people newly diagnosed with extensive-stage small cell lung cancer. The goal is to see if adding YSQTG improves outcomes for patients with a specific traditional Chinese medicine pattern.

Beijing, Chaoyang
NCT06907602Recruiting· Phase 2/Phase 3
Optimizing treatment before surgery for advanced esophageal cancer

This trial tests different combinations of treatments given before surgery for a type of esophageal cancer called squamous cell carcinoma. It aims to find the best approach to shrink the tumor and improve outcomes for patients whose cancer has not spread to distant organs.

Beijing, Beijing Municipality

Hear when a new Esophageal Squamous Cell Carcinoma (ESCC) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.