Short-course radiation plus immunotherapy and chemo for esophageal cancer
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial tests a new combination of short-course radiation, an immunotherapy drug (tislelizumab), and chemotherapy before surgery for esophageal cancer. It aims to shrink tumors and improve surgical outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have esophageal squamous cell carcinoma that can be removed with surgery and has not spread to distant organs.
- You are between 18 and 75 years old.
- You have not had any prior treatment for this cancer.
- You are in good general health (able to care for yourself) and have adequate organ function.
- You have not had prior treatment with PD-1/PD-L1 inhibitors or other immune-targeting drugs.
- You do not have an active autoimmune disease, uncontrolled heart disease, or active infections like HIV, hepatitis B/C, or tuberculosis.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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