Study of camrelizumab plus chemo before surgery for esophageal cancer
Part of Cancer, Digestive system clinical trials.
This trial tests whether giving the immunotherapy drug camrelizumab together with chemotherapy before surgery can help people with esophageal cancer avoid needing full removal of the esophagus. It aims to preserve the esophagus while still treating the cancer effectively.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with esophageal cancer that has not spread to other organs.
- You are between 18 and 75 years old.
- You are healthy enough for daily activities (ECOG score 0 or 1).
- You have not had any prior cancer treatment for this esophageal cancer, such as radiation, chemo, or surgery.
- Your lungs, kidneys, liver, and blood counts are within acceptable ranges.
- You are willing to use effective birth control during treatment and for 6 months after.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests a combination of two targeted drugs (nimotuzumab and camrelizumab) plus standard chemotherapy before surgery for people with esophageal squamous cell carcinoma. The goal is to see if this approach helps shrink the tumor and improve outcomes.
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This Phase 3 trial compares two ways of treating resectable esophageal squamous cell cancer: (1) camrelizumab plus chemotherapy before surgery versus (2) chemo-radiation. It aims to see whether adding camrelizumab before surgery can improve outcomes for people who are planned to have their tumor surgically removed.
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