Experimental malaria infection in healthy adults
Part of Infections clinical trials.
This study tests a genetically modified malaria parasite that is intentionally given to healthy volunteers through a mosquito bite. The goal is to see if it is safe and to learn how the immune system responds, which could help develop a malaria vaccine.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be aged 18 to 55 and in good general health.
- You need to have O negative blood type.
- You must never have had malaria or a malaria vaccine.
- You need to be willing to have blood samples collected and stored for future research, and to delay blood donations for at least 6 months after the study ends.
- You must not have traveled to or lived in a malaria-endemic area in the past 12 months (or plan to during the study), and must not have lived in such an area for more than 10 years in your life.
- If you are a woman who could become pregnant, you must agree to use effective birth control and have a negative pregnancy test.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new investigational drug (GSK4425689A) for the first time in humans. It is a healthy volunteer study to check the safety, side effects, and how the drug moves through the body. It may help in the future development of treatments for malaria.
This study tests a new malaria vaccine in healthy adults. You will receive the vaccine and then be exposed to the malaria parasite in a controlled setting to check if the vaccine protects you.
This trial tests a new malaria drug (MMV055), alone or with another drug (MMV371), to see if it is safe and how the body processes it. It is for healthy people who want to help find new malaria treatments.
This study tests a new long-acting injection to prevent malaria. It checks safety and how the body handles the drug in healthy adults and adolescents in Rwanda.
This trial tests a new combination of experimental malaria vaccines to see if they are safe and help protect against malaria. It includes both adults and young children in malaria-affected areas.
This study tests a new malaria pill in adults with uncomplicated malaria (mild form). The pill aims to treat the infection, and participation involves monitoring and follow-up visits.
Hear when a new Malaria Falciparum trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.