First-in-human safety study of an investigational drug in healthy adults
Part of Infections clinical trials.
This study tests a new investigational drug (GSK4425689A) for the first time in humans. It is a healthy volunteer study to check the safety, side effects, and how the drug moves through the body. It may help in the future development of treatments for malaria.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 65 years old.
- Your weight should be between 110 and 220 pounds, and your body mass index (BMI) must be in a healthy range of 18 to 32.
- You must be in good general health with no major medical conditions such as heart disease, diabetes, or autoimmune disorders.
- If you are female, you must not be able to become pregnant (for example, surgically sterile or past menopause), and you must not be pregnant or breastfeeding.
- You cannot have a history of malaria, or have received a malaria vaccine, or taken part in malaria-related studies before.
- You must not have used prescription or over-the-counter medications, herbal supplements, or CBD products within 14 days before the study starts.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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