Clinical trials
Malaria Falciparum clinical trials
Below are recruiting malaria falciparum clinical trials, each written for real people, not researchers. We’re tracking 17 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06529237Recruiting
Malaria study for children and pregnant women in Mozambique
This study looks at how malaria spreads in Mozambique by testing children and pregnant women with fever. If you or your child may have malaria, participating could help researchers understand and fight the disease better.
Manhiça, Maputo ProvinceAges 6 months+ - NCT07389057Recruiting
Malaria prevention study with combined medicines in Ghana
This trial tests if giving two malaria medicines together (dihydroartemisinin piperaquine and primaquine) to everyone in a community can help reduce malaria. It is for people living in high-risk areas in eastern Ghana.
Accra, Eastern RegionAges 3 months+ - NCT05750628RecruitingPhase 2
Testing malaria medicines in uncomplicated falciparum malaria
This trial studies how well and how safely different anti-malaria medicines work for people who have uncomplicated malaria caused by Plasmodium falciparum. You may be eligible if you have a confirmed infection with a certain parasite level and do not have signs of severe disease or major health conditions.
BanforaAges 2–100 - NCT07749911Recruiting
Vaccine effectiveness study for malaria in young children
This study looks at how well the R21/Matrix-M malaria vaccine works in real-life settings for children under 5. If your child is eligible for the vaccine and has a fever, they may be able to join and help us understand the vaccine's impact.
Boromo, Boucle MouhounAges 5 months–5 years - NCT05911828RecruitingPhase 1
Oral malaria pill study in adults without symptoms
This Phase 1 study tests how safe a combination oral medicine (ZY19489 with ferroquine) is in adults who carry malaria in their blood but have no symptoms. It also studies how the body absorbs and processes the medicines.
LambarénéAges 18–55 - NCT06923592RecruitingPhase 3
Blood test and treatment for vivax malaria in Ethiopia and Madagascar
This trial tests whether using a blood test to find and treat people infected with a type of malaria called Plasmodium vivax can reduce the spread of the disease. It may help you and your community stay healthier.
Addis AbabaAges 1 year+ - NCT07009847Recruiting
Study of the R21/Matrix-M malaria vaccine
This study looks at how well the R21/Matrix-M malaria vaccine works and how safe it is in children who received it. It compares children who got malaria (or died) to healthy children who also got the vaccine.
Bousse, Burkina FasoAges 5 months+ - NCT06958198RecruitingPhase 1
Testing a new multi-stage malaria vaccine in adults and children
This trial tests a new combination of experimental malaria vaccines to see if they are safe and help protect against malaria. It includes both adults and young children in malaria-affected areas.
Siglé, Boulkiemdé ProvinceAges 5 months–35 years - NCT07559370RecruitingPhase 2
Imatinib Plus Artemether-Lumefantrine for Uncomplicated Malaria
This trial tests whether adding a cancer drug called imatinib to standard malaria treatment works better and is safe. Researchers will enroll adults and children with uncomplicated malaria caused by P. falciparum parasites and monitor them in the hospital for 2–3 days.
KisumuAges 1–55 - NCT06862453RecruitingPhase 1
Safety of a new malaria vaccine in healthy adults
This study tests a new malaria vaccine in healthy adults. You will receive the vaccine and then be exposed to the malaria parasite in a controlled setting to check if the vaccine protects you.
TübingenAges 18–45 - NCT05790889RecruitingPhase 1/Phase 2
Study of an experimental malaria vaccine in babies in Burkina Faso
This Phase 1/2 study tests a new vaccine meant to protect young children against malaria. If you qualify, your baby would get the study vaccine and be followed for about 12 months to check safety and early signs of protection.
Siglé, Boulkiemdé ProvinceAges 5 months–1.4 years - NCT05951595RecruitingPhase 3
Testing three malaria medicines together versus two
This study compares a combination of three medicines to treat uncomplicated malaria, to see if it works as well and is as well tolerated as a two-medicine combination. You may join if you have a specific type of malaria infection in a mild form and meet safety requirements.
Ruhuha, Eastern ProvinceAges 6 months+ - NCT07011511RecruitingPhase 1
Testing a new malaria drug in healthy volunteers
This trial tests a new malaria drug (MMV055), alone or with another drug (MMV371), to see if it is safe and how the body processes it. It is for healthy people who want to help find new malaria treatments.
NottinghamAges 18–60 - NCT07670377RecruitingPhase 1
Drug interaction study of GSK3772701 in healthy adults aged 18-55
This trial tests how a new drug (GSK3772701) interacts with another common drug (midazolam) in healthy volunteers. It aims to see if one affects how the other works in the body and will help determine safe dosing for future studies.
Miami, FloridaAges 18–55 - NCT06068530RecruitingPhase 4
Mass malaria vaccine and drug campaign in Bangladesh villages
This trial is testing whether giving a malaria vaccine and a malaria drug together to whole villages in Bangladesh can help stop the spread of malaria and protect the entire community. It is open to nearly everyone living in selected villages, including children and adults.
BāndarbanAges 6 months+ - NCT07675785RecruitingPhase 2
Malaria Vaccine Study for Women Who Could Become Pregnant in Mali
This study tests an experimental malaria vaccine called PfSPZ-LARC2. Researchers want to learn if it is safe and effective for women who could become pregnant, especially in Mali where malaria is common. You would receive several doses of the vaccine and be followed for a few months.
BamakoAges 18–38 - NCT07385287RecruitingPhase 2
Malaria vaccine trial for healthy adults in Burkina Faso
This study tests a new malaria vaccine called PfSPZ-LARC2 in healthy adults living in Burkina Faso. If you qualify, the vaccine is given to see if it can protect you from malaria.
OuagadougouAges 18–50
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Common questions
- Are there clinical trials for malaria falciparum?
- Yes. Clin2 currently lists 17 recruiting malaria falciparum studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a malaria falciparum trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a malaria falciparum trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.