Lung deflation procedure for severe emphysema
Part of Lungs & breathing clinical trials.
This study tests a bronchoscopic treatment to release trapped air in severely hyperinflated lungs caused by emphysema. It may help you breathe easier if you have advanced COPD and meet specific lung function and imaging criteria.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 40 and 84 years old.
- Your body mass index (BMI) is between 18 and 32.
- You have completed a pulmonary rehab program in the last year.
- You have moderate to severe shortness of breath (mMRC score of 2 or higher).
- You can walk at least 100 meters in 6 minutes.
- Your lung function tests show severe air trapping and moderate to severe COPD (FEV1 15-45% predicted, RV/TLC ≥ 0.55), and a CT scan shows significant emphysema in both lungs.
- You must have stopped smoking (including vaping, marijuana) for at least 4 months and agree not to smoke during the study.
- You are up to date on recommended vaccines (pneumonia, flu, RSV if over 60, and COVID-19) or have a medical reason not to get them.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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