Targeted therapy plus chemo for advanced pancreatic cancer
Treatments studied
Part of Cancer clinical trials.
This study tests a new targeted drug called sotorasib combined with standard chemotherapy for people with advanced pancreatic cancer that has a specific KRAS G12C mutation. The goal is to see if the combination works better than chemotherapy alone.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older and willing to give informed consent.
- You have a specific type of pancreatic cancer (called KRAS G12C positive) that is locally advanced or has spread to other parts of the body.
- You have not had any prior chemotherapy for this advanced cancer (except possibly a short course of standard treatment while waiting for study enrollment).
- You are able to swallow pills, keep a daily medication diary, and have adequate organ function as shown by blood tests.
- You are not pregnant or breastfeeding, and you agree to use effective contraception if applicable.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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