Improving kidney transplant with a single injection of a protective protein
Part of Genetic & congenital, Heart & circulation, Immune system & allergy, Skin clinical trials.
This trial tests whether a single injection of C1 esterase inhibitor into a donated kidney during preservation can improve transplant outcomes. It is for adults on dialysis waiting for a deceased-donor kidney who meet specific blood and tissue matching requirements.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are on chronic dialysis and on the waiting list for a deceased-donor kidney transplant.
- Your blood type is compatible with the donor's blood type.
- You have no antibodies that attack the donor kidney, as shown by a recent blood test.
- You are willing to use effective birth control for at least 12 months after transplant if you can have children.
- You have a normal blood clotting ability and no history of blood clotting problems (except for minor clotting from dialysis access or superficial veins).
- Your donor kidney must be stored on a cold perfusion machine for at least 12 hours before transplant.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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