Testing AGB101 for brain health in older adults
Part of Brain & nervous system, Mental health clinical trials.
This study tests whether a medication called AGB101 (levetiracetam) can reduce overactivity in the hippocampus, a brain area important for memory. It is for healthy older adults who do not have memory problems, to see if the drug can help keep the brain working well.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 50 and 80 years old.
- You have a study partner (a friend or family member) who spends at least 2 hours per week with you and can help the study team.
- You have normal memory and thinking skills for your age, as shown by a memory test.
- You are willing to have an MRI brain scan (no metal implants, pacemakers, or other MRI restrictions).
- You are not taking certain medications like blood thinners or seizure medicines, and you have not had major depression or other serious mental health conditions recently.
- You are willing to give a blood sample for genetic testing (ApoE).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how well people with Alzheimer’s disease (AD) or mild cognitive impairment (MCI) perform on standardized memory/brain tests. It may help researchers understand changes over time, and whether certain types of brain signals or test results track with the condition.
This study tests a new medication, CORT108297, that may help protect the brain from the harmful effects of stress in people at risk for Alzheimer's disease. It is looking for adults age 55 and older who either have mild memory problems or are healthy but have a family history, APOE4 gene, or memory concerns.
This trial tests if a medication called levetiracetam (a drug usually used for seizures) can help protect memory in people who are at higher risk for Alzheimer's but do not yet have memory problems. It involves brain scans and cognitive tests to see if the drug can reduce overactive brain activity linked to memory loss.
This trial tests a supplement called AP-Brain to see if it helps with memory and thinking in healthy middle-aged and older adults who notice memory problems. You would take different doses of the supplement or a placebo for several weeks and complete memory tests.
This trial tests a new medicine, VHB937, in people with early Alzheimer's (mild cognitive impairment or mild dementia). The goal is to see if it can slow down memory loss and thinking problems.
This study looks at healthy brain aging in older adults. It involves brain scans, blood tests, and regular check-ins to understand how memory and thinking change over time.
Hear when a new Dementia trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.