Switching antipsychotics to xanomeline/trospium for schizophrenia
Treatments studied
Part of Mental health clinical trials.
This study tests how well people with schizophrenia can switch from their current antipsychotic medication to a new combination drug, xanomeline/trospium, either quickly or slowly over 8 weeks. It may be an option if your current medication causes side effects or is not working well enough.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 65 years old.
- You have a diagnosis of schizophrenia and are currently stable.
- You have been taking one of these oral antipsychotics for at least 6 weeks: risperidone, paliperidone, aripiprazole, ziprasidone, quetiapine, lurasidone, lumateperone, brexpiprazole, or olanzapine.
- You are willing to stop your current antipsychotic and start the study drug.
- You do not have severe kidney, liver, bladder, or bowel problems, and you are not at high risk for urinary retention or constipation.
- You are not pregnant, breastfeeding, or planning to become pregnant during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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