Clin2
NCT06925555Possibly a fitNot yet recruiting

Brentuximab vedotin with R-CHP for EBV-positive DLBCL

EBV-Positive Diffuse Large B-Cell Lymphoma, NosBrentuximab Vedotin

Part of Digestive system clinical trials.

This trial tests a new combination of drugs for people with a type of lymphoma called EBV-positive DLBCL that has not been treated before. The goal is to see if adding brentuximab vedotin to the standard R-CHP chemotherapy can improve outcomes.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
25 people
Ages
18 years to 70 years
Study type
Interventional

Who can take part

  • You have been diagnosed with EBV-positive diffuse large B-cell lymphoma (DLBCL)
  • You are between 18 and 70 years old
  • You have measurable disease on a PET/CT scan
  • You are generally in good health (ECOG performance status 0-2)
  • Your organs (liver, kidneys, heart, bone marrow) are functioning adequately
  • You have not had prior treatment for this lymphoma

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07178457Not yet recruiting· Phase 3
Brentuximab after stem cell transplant for mycosis fungoides

This trial tests whether giving a drug called brentuximab vedotin after a stem cell transplant can help keep your lymphoma in check and prevent it from coming back. It is for people with a specific type of lymphoma (mycosis fungoides) that has been hard to treat and who have recently had a transplant.

NCT06468943Enrolling by invitation· Phase 2
New drug combo for non-GCB diffuse large B-cell lymphoma

This trial tests a combination of three targeted drugs (polatuzumab vedotin, zanubrutinib, and R-CHP) for people newly diagnosed with a specific subtype of DLBCL called non-GCB. The goal is to see if this powerful mix can work better than standard treatment.

Suzhou, Nanjing
NCT07744737Not yet recruiting· Phase 2
Pirtobrutinib plus R-CHOP for untreated non-GCB DLBCL

This trial tests a new drug called pirtobrutinib combined with standard chemotherapy (R-CHOP) for people with a type of large B-cell lymphoma that hasn't been treated before. The goal is to see if adding this drug helps the treatment work better.

Nanjing, Jiangsu
NCT07744724Not yet recruiting· Phase 2
Pirtobrutinib plus Pola-R-CHP for newly diagnosed non-GCB DLBCL

This trial tests a new combination of targeted therapy (pirtobrutinib) with standard chemotherapy (Pola-R-CHP) for people newly diagnosed with a type of large B-cell lymphoma that is not the germinal center B-cell subtype. The goal is to see if adding pirtobrutinib helps the treatment work better.

Nanjing, Jiangsu
NCT07624838Recruiting
Brentuximab vedotin plus chemotherapy for CD30+ T-cell lymphoma

This study looks at how well a combination drug treatment (brentuximab vedotin plus chemotherapy) works for patients with rare T-cell lymphomas in real-world clinical practice in Spain. It focuses on patients receiving this as their first treatment.

A Coruña, A Coruña
NCT06761911Not yet recruiting· Phase 4
Study of brentuximab vedotin for relapsed hodgkin lymphoma

This trial tests a drug called brentuximab vedotin (BV) for people whose hodgkin lymphoma has come back or did not respond to earlier treatment. The goal is to see if BV can help control the cancer.

Hear when a new Brentuximab Vedotin trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.