Platelet-rich plasma for complete loss of smell
Treatments studied
Part of Brain & nervous system clinical trials.
This study tests whether an injection of your own platelet-rich plasma (a concentrated part of your blood that helps healing) can improve your sense of smell. It is designed for people who have completely lost their smell (anosmia) without a known cause like injury or nasal blockage.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are aged 18 to 50 years old.
- You have lost your sense of smell completely, confirmed by a low score (10 or less out of 40) on a smell test.
- Your nasal passages are open and clear, with no blockages from sinusitis, polyps, a deviated septum, or enlarged turbinates.
- Your smell loss is not caused by a head injury.
- You do not have a blood disease, diabetes, or high blood pressure.
- You have not taken any medications that affect blood clotting or bone marrow in the last 2 weeks.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether injecting a concentrated solution from your own blood, called platelet-rich plasma (PRP), into the nose can help restore the sense of smell in people with smell dysfunction. It may offer a new treatment option for those who haven't improved with other therapies.
This trial tests whether a treatment made from your own blood (platelet-rich plasma) can help restore your sense of smell after an infection, and whether adding insulin makes it work better. You’ll receive the treatment inside your nose, and the study will compare the two options.
This study tests a smell training program for people who lost their sense of smell after a viral infection like a cold or flu. If you've had smell loss for more than 3 months but less than 2 years, this training might help you regain your sense of smell.
This trial tests if osteopathic manipulative treatment (OMT) can help people regain their sense of smell after COVID-19. OMT is a hands-on therapy used by osteopathic doctors to improve body function.
This study uses brain imaging and electrical recordings to understand the brain's role in smell loss from any cause—like COVID, sinus problems, or chemotherapy. You may be eligible if you have any degree of smell loss lasting under a year.
This trial studies whether structured smell (olfactory) training can improve ongoing smell problems after COVID-19. It may help people whose sense of smell hasn’t fully returned long after the infection.
Hear when a new Anosmia trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.