Clin2
NCT06937385Possibly a fitNot yet recruiting

Neck muscle injection vs IV meds for headache in the ER

HeadacheMigraineTension HeadacheOccipital Neuralgia

Part of Brain & nervous system, Pain clinical trials.

This trial compares a numbing injection into the neck muscles with standard IV medications to treat headaches in the emergency room. The goal is to see which works better and faster for relieving pain.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
100 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be able to give your own permission to join the study.
  • You need to be able to speak and understand English.
  • Your headache must not be caused by an injury (like a fall or car accident).
  • Your headache pain should be at least a 5 out of 10 on the pain scale.
  • You must not have a bleeding disorder or be taking blood thinners.
  • You cannot be pregnant, breastfeeding, or in prison.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT04930887Recruiting· Phase 2
Numbing injection in the face to ease craniofacial pain

This trial tests whether an injection of a numbing medicine (bupivacaine) guided by an endoscope can reduce craniofacial pain. It may help people with certain headache or facial pain conditions by targeting the pain area more precisely.

Stanford, California
NCT06621329Recruiting· Phase 2/Phase 3
Numbing shot for headache after brain bleed

This trial tests a numbing injection inside the nose to quickly relieve severe headaches caused by a brain bleed (subarachnoid hemorrhage). It may help reduce pain without strong medicines.

Sacramento, California
NCT07632820Recruiting· Phase 4
Nerve Block vs. Injection for Upper Back Muscle Pain

This study compares two ways to treat chronic muscle pain in the upper back: a nerve block (numbing injection near the spine) and trigger point injections (shots directly into painful muscle knots). The goal is to see which approach works better for long-lasting relief.

Jacksonville, Florida
NCT05605639Recruiting· Phase 4
Study tests a targeted injection for neck pain

This trial studies whether an injection near the phrenic nerve can help people with neck pain. It is only for certain types of neck/diaphragm-related problems and excludes people with nerve, injury, cancer, infection, or autoimmune causes.

Dos Hermanas, Seville
NCT07595406Not yet recruiting
Comparing two neck pain injection techniques

This study compares two different injection methods to treat chronic neck pain coming from the small joints in your neck. Both methods use numbing medication to reduce pain; researchers want to see which one works better.

Ankara, Ankara
NCT05734625Recruiting· Phase 2
Nerve block injections for episodic migraine pain relief

This Phase 2 trial tests whether nerve block injections can reduce pain from episodic migraines. It may help some people who get frequent migraine attacks but are not also using certain migraine preventions or strong pain medicines.

Rochester, Minnesota

Hear when a new Headache trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.