Comparing two ways to give an antibiotic for serious infections in the ICU
Part of Infections clinical trials.
This trial tests whether giving the antibiotic ceftazidime-avibactam continuously or intermittently works better for ICU patients with severe infections caused by drug-resistant bacteria. The goal is to see which method improves outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 85 years old
- You are in the intensive care unit (ICU)
- You have an infection caused by hard-to-treat bacteria (carbapenem-resistant organisms) and are already on ceftazidime-avibactam
- You have at least one sign of organ failure in the last day, like low blood pressure, needing a breathing machine, or high creatinine levels
- You have not been on ceftazidime-avibactam for more than 48 hours for this infection
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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