Comparing two ways to give an antibiotic for severe ICU infections
Part of Infections clinical trials.
This study tests two ways of giving the antibiotic ceftazidime/avibactam (as a continuous drip or as intermittent shots) to patients in the intensive care unit with severe infections. The goal is to see which method works better or is safer for critically ill patients.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 to 85 years old.
- You must be in the intensive care unit (ICU) because of a severe infection.
- Your infection must be caused by certain bacteria (Klebsiella pneumoniae with OXA-48 or Pseudomonas aeruginosa).
- You must not be allergic to ceftazidime/avibactam or similar antibiotics.
- If you are a woman, you must not be pregnant or breastfeeding.
- You cannot have a weakened immune system (severe neutropenia), HIV/AIDS, or a history of cancer.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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