Zanzalintinib vs Everolimus for Neuroendocrine Tumors
Treatments studied
Part of Cancer, Digestive system, Hormones & metabolism clinical trials.
This trial compares a new targeted therapy (zanzalintinib) with an existing drug (everolimus) for people with advanced neuroendocrine tumors (NETs). It aims to see which treatment works better and may offer a new option for patients whose cancer has grown despite previous treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a type of neuroendocrine tumor (NET) that started in your pancreas or elsewhere outside the pancreas, and it is well-differentiated (low to medium grade).
- Your cancer has grown or spread and cannot be removed by surgery.
- You have had scans (CT or MRI) in the last 12 months showing your cancer has gotten worse.
- You have at least one tumor that can be measured on scans.
- You have not taken a VEGFR-targeting TKI (like sunitinib) or an mTOR inhibitor (like everolimus) before.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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