YAP1 blocker in surgical wound healing
Treatments studied
Part of Skin clinical trials.
This study tests a medication called Verteporfin, which may improve how surgical wounds heal. It is given during surgery to remove a type of skin cancer or precancerous lesion, and the researchers will see if it helps the wound heal better.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 55 years old.
- You have a melanoma in situ or a severe atypical mole that was completely removed, and you are scheduled for a wider excision (a 5 mm margin) within the recommended time.
- The original scar is between 15 mm and 50 mm long.
- The original lesion was on your back (or another body area if the study group isn't filled quickly).
- You are not allergic to eggs or to Verteporfin, and you do not have liver problems, porphyria, or certain skin or connective tissue disorders.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
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This trial tests a new way to help wounds heal by using a special material that supports the skin's natural repair process. It is for people with different types of wounds that need surgery, like burns, cuts, or chronic sores.
This study looks at how a wound dressing or treatment affects healing in surgical cuts that are closed with sutures or similar methods. You may be able to join if you’re having a skin surgery on the neck, trunk, or arms/legs with a long enough wound you can follow up on.
This study tests a special fiber mat called Restrata that is placed in the wound after skin cancer removal to help it heal. The mat acts as a scaffold for new skin growth and may help close the wound without needing a skin graft.
This study tests a treatment that uses plasma (a part of your blood) to improve the look and feel of scars. It may help reduce symptoms like itching or pain and make scars less noticeable.
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