YAP1 inhibitor for skin wound healing after mole removal
Treatments studied
Part of Skin clinical trials.
This trial tests a drug called Verteporfin, applied to surgical wounds after removing a skin lesion (like a mole) to see if it helps healing and prevents scarring. It's for people who need a small second surgery to make sure all abnormal cells are gone.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You had a skin lesion (melanoma in situ or severe dysplastic nevus) completely removed before, and now need a safety margin excision (5 mm extra around the scar).
- Your original scar must be between 15 mm and 50 mm long and located on your back (or sometimes another spot if allowed).
- You are between 18 and 55 years old.
- You are not allergic to eggs, Verteporfin, or any of its ingredients.
- You do not have certain liver problems, porphyria, or skin/scarring conditions (like keloids, scleroderma, or Ehlers-Danlos syndrome).
- You are not pregnant, breastfeeding, or planning pregnancy in the next 6 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a gel called LUT017 to see if it improves how skin wounds heal after removing benign skin lesions like moles or seborrheic keratoses. If you are a healthy adult having at least two such lesions removed, you may be able to join.
This study tests if a drug called verteporfin, given during a tummy tuck, can help prevent scars from forming. It is for adults having planned tummy tuck surgery who are generally healthy and have lighter to medium skin tones.
This early study tests whether a medicine called SADBE can help treat congenital (from birth) melanocytic nevi—large birthmark moles—before planned non-urgent removal. The goal is to see if SADBE is safe and helpful for these large moles.
This study tests a device that uses a special light to image skin lesions after applying an FDA-approved cream. It aims to see if the device can help doctors see benign skin growths more clearly before they are removed.
This trial is testing a new wound dressing (CAMP) plus standard care versus standard care alone for healing skin cancer surgery wounds. It's for people who have had Mohs surgery and whose wound can heal on its own without a flap or graft.
This trial tests a liquid containing tiny particles called exosomes that may help wounds heal. Healthy volunteers apply it to their skin to see if it's safe for future use after surgery.
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