Study of Flecainide for Frequent Extra Heartbeats
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests whether the medication flecainide can reduce frequent extra heartbeats (called PVCs) that come from normal heart tissue, and may help prevent or reverse heart muscle problems caused by these extra beats.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have frequent extra heartbeats (more than 5% of your total heartbeats) recorded on a 24-hour heart monitor.
- Your heart structure and function are normal on an ultrasound of the heart (echocardiogram).
- You have no scar tissue or damage in your heart muscle as seen on a special heart MRI.
- A coronary angiography (heart artery X-ray) shows no blockages.
- Your blood tests for electrolytes and kidney function are normal.
- You are willing to follow the study schedule and take the medication as directed.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether treating frequent PVCs (extra heartbeats) can help protect the heart’s pumping strength in people who currently feel fine. It specifically looks at patients with a high PVC burden but normal heart function, using a preventative approach.
This study compares two treatments for people with frequent extra heartbeats (PVCs): a procedure called catheter ablation or medications. It aims to find which works better and has fewer side effects.
This study looks at how extra heartbeats (called premature ventricular complexes or PVCs) affect physical abilities. It compares people with troublesome PVCs to healthy volunteers to understand the impact on daily function.
This trial tests whether a gentle nerve-stimulation device worn on the ear can reduce dangerous heart-rhythm problems. There are two groups: one for people with frequent extra heartbeats (PVCs) and one for people with a defibrillator who have had repeated episodes of a more serious rhythm problem (VT).
This trial tests a non-surgery treatment (using a skin patch) for people who have frequent extra heartbeats coming from the heart’s lower chambers. It’s meant to see whether the patch reduces symptoms or abnormal heart rhythm compared with usual care.
This trial compares two medicines—flecainide and amiodarone—to help restore normal rhythm during an emergency visit for paroxysmal atrial fibrillation (a-fib). It’s aimed at people who also have coronary artery disease but no ongoing (residual) heart ischemia, and who have enough heart pumping strength.
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