Study of Flecainide for Frequent Extra Heartbeats
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests whether the medication flecainide can reduce frequent extra heartbeats (called PVCs) that come from normal heart tissue, and may help prevent or reverse heart muscle problems caused by these extra beats.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have frequent extra heartbeats (more than 5% of your total heartbeats) recorded on a 24-hour heart monitor.
- Your heart structure and function are normal on an ultrasound of the heart (echocardiogram).
- You have no scar tissue or damage in your heart muscle as seen on a special heart MRI.
- A coronary angiography (heart artery X-ray) shows no blockages.
- Your blood tests for electrolytes and kidney function are normal.
- You are willing to follow the study schedule and take the medication as directed.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares two ways to treat premature ventricular contractions (extra heartbeats that can cause symptoms). One approach is a catheter ablation (a procedure that destroys the tissue causing the extra beats), and the other is using anti-arrhythmic drugs (medications to control the rhythm). If you have frequent PVCs and a healthy heart, this trial could help you find the best treatment.
This study tests two different medicines to see if giving them early can prevent your heart from weakening over time when you have frequent extra beats. You may join if you have no symptoms from these beats and your heart function is still normal.
This trial tests a non-invasive nerve stimulation treatment (using a small device on the ear) to reduce dangerous heart rhythm problems. It is for people with frequent premature heartbeats (PVCs) or with an implanted defibrillator who have had repeated episodes of a fast heart rhythm (VT).
This trial tests a non-surgery treatment (using a skin patch) for people who have frequent extra heartbeats coming from the heart’s lower chambers. It’s meant to see whether the patch reduces symptoms or abnormal heart rhythm compared with usual care.
This study looks at whether certain foods or diet patterns relate to extra heartbeats called PVCs. It compares people with many PVCs to healthy people to see if diet might play a role.
This trial compares two medicines—flecainide and amiodarone—to help restore normal rhythm during an emergency visit for paroxysmal atrial fibrillation (a-fib). It’s aimed at people who also have coronary artery disease but no ongoing (residual) heart ischemia, and who have enough heart pumping strength.
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