Managing Blood Thinners Before High-Risk Surgery
Part of Heart & circulation clinical trials.
This study looks at how to safely manage your blood thinner (DOAC) around the time of a planned, high-bleed-risk surgery or procedure involving a spinal needle. The goal is to find the best way to stop and restart your medication to prevent bleeding and clotting problems.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older.
- You take a full dose of one of these blood thinners: apixaban (Eliquis), dabigatran (Pradaxa), edoxaban (Savaysa/Lixiana), or rivaroxaban (Xarelto).
- You take it for atrial fibrillation (a type of irregular heartbeat) or for a blood clot in your leg or lung.
- You have a planned surgery or procedure that has a high risk of bleeding, or that involves a spinal needle (epidural, spinal block).
- You do not have severe kidney problems, and you are able to give consent and stay in contact for follow-up.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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