Clin2
NCT06964269Possibly a fitRecruiting

Acthar Gel for dry eye and autoimmune disease

Autoimmune DiseasesDry EyeNeurotrophic Keratitis

Part of Eyes & vision, Immune system & allergy clinical trials.

This trial tests a new injectable medicine, Acthar Gel, for moderate to severe dry eye and eye pain linked to autoimmune disease. It aims to see if the drug can relieve these symptoms safely.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
20 people
Ages
18 years to 85 years
Study type
Interventional

Who can take part

  • You are between 18 and 85 years old.
  • You have had dry eye for at least 6 months.
  • You have an autoimmune disease (like Sjögren's, lupus, or rheumatoid arthritis).
  • You have corneal nerve damage causing eye pain, confirmed by a special microscope.
  • A numbing eye drop relieves your eye pain for at least 15 minutes.
  • You have not used the study drug (Acthar Gel) before.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07560735Not yet recruiting· Phase 4
Lifitegrast eye drops for dry eye disease evaluation

This study tests whether lifitegrast eye drops (a medication that reduces eye inflammation) help people with moderate to severe dry eye disease. Researchers will use a special microscope to examine your eye surface before and after treatment.

Nashville, Tennessee
NCT07413172Recruiting· Phase 2
Testing serum tears for severe dry eye

This study tests whether eye drops made from your own blood serum (with a natural lubricant) can relieve moderate-to-severe dry eye better than a standard salt solution. If you have dry eye from certain immune conditions or nerve damage, this may help find a more effective treatment.

Miami, Florida
NCT07329712Recruiting
Light therapy for dry eye: tear protein study

This trial tests whether low-level light therapy can improve dry eye disease by measuring changes in tear proteins. It may help people with chronic dry eye who are interested in a non-drug treatment.

Singapore
NCT07625124Not yet recruiting· Phase 2
Testing a new eye drop for dry eye disease

This study tests whether RCI001, a new eye drop treatment, can help people with dry eye disease. If you've had dry eye symptoms for at least 6 months and are interested in trying a new treatment, this trial may be for you.

NCT06903611Not yet recruiting· Phase 3
Eye drop from human platelets for dry eye

This study tests an experimental eye drop made from human platelets (blood cells that help healing) for people with moderate to severe dry eye. The drop is compared to a placebo (fake drop) to see if it improves eye comfort and surface health.

NCT06942793Not yet recruiting· Phase 3
Eye drop gel test for dry eye patients

This trial tests a new eye drop gel (CsA-PG) for people with dry eye disease. Participants must have had dry eyes for at least 6 months and meet specific eye exam scores. The study checks if the gel can improve symptoms and eye health.

Hear when a new Autoimmune Diseases trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.