Gene therapy study for nerve pain from small fiber neuropathy
Part of Brain & nervous system clinical trials.
This trial tests a new gene therapy called ST-503 for people with long-lasting nerve pain from small fiber neuropathy that hasn't improved with standard treatments. The study will check if the treatment is safe and tolerable.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with small fiber neuropathy (SFN) with chronic nerve pain.
- Your pain has not responded to at least 2 of the 3 main types of standard pain medications for at least 6 months.
- You do not have antibodies against the AAV9 virus used in this gene therapy (a blood test will check this).
- You are not currently using opioid painkillers unless you have been on a stable dose for at least 3 months and won't need to increase it.
- You have no history of alcohol or drug abuse in the last 2 years, and you do not use cannabis products.
- You have no active infections, serious liver problems, or a history of cancer (except minor skin cancer or fully treated early breast cancer) in the last 5 years.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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