Deep brain stimulation for apathy in Parkinson's disease
Part of Brain & nervous system clinical trials.
This trial is testing whether a type of deep brain stimulation (called VC/VS-DBS) can help people with Parkinson's disease who have severe apathy (a loss of interest or motivation) that hasn't gotten better with medication. The goal is to see if this treatment can improve motivation and quality of life.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a confirmed diagnosis of Parkinson's disease.
- You have severe apathy that has lasted at least 2 years and hasn't improved with standard treatments.
- You do not have dementia or major memory problems.
- You have a caregiver or family member who can help with surveys and interviews.
- You are able to give informed consent and are willing to follow the study procedures.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether a non-invasive brain stimulation treatment called TMS (transcranial magnetic stimulation) can help improve apathy, or loss of motivation, in people with Parkinson's disease. You must have had symptoms for at least 4 years and be on stable Parkinson's medications.
This trial tests whether deep brain stimulation (DBS) can help people with early-stage Parkinson's disease. If you have Parkinson's for less than 4 years and your medications work well, this study may help slow the need for higher medication doses.
This study looks at factors that predict how well deep brain stimulation (DBS) works for people with Parkinson's disease. If you are considering DBS, joining this research could help doctors better understand who benefits most from the procedure.
This study uses special recordings during deep brain stimulation surgery to better understand how movement gets easier in Parkinson’s disease. It may help researchers improve how this therapy is used for advanced symptoms.
This study tests whether a gentle, low-voltage electrical stimulation (tDCS) can help improve depression in people with Parkinson's disease. It involves coming to the lab for sessions where a small device sends a mild current to your brain, and you'll also have an EEG (a non-invasive brain wave recording).
This trial tests whether a gentle electrical stimulation on your ear (taVNS) can help improve low motivation (apathy) in people with Parkinson's. It also uses MRI scans to see how the treatment affects the brain.
Hear when a new Deep Brain Stimulation trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.