Botulinum toxin injection for severe period pain
Treatments studied
Part of Pain, Women’s health & pregnancy clinical trials.
This trial tests whether injecting botulinum toxin into the uterine muscle during a hysteroscopy can reduce severe period pain or chronic pelvic pain that hasn't improved with standard treatments. It may be an option for women who have tried hormonal therapy and pain relievers without success.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are an adult woman who has not reached menopause.
- You have severe period pain (average pain score 6 or higher out of 10 over the last 3 months) or chronic pelvic pain similar to period pain while on hormonal treatment.
- Standard treatments like hormonal therapy and pain relievers (including NSAIDs) have not worked for you.
- You have had a pelvic MRI in the past year that shows no signs of deep endometriosis or endometriomas.
- You are willing to use effective birth control (such as hormonal pills, IUD, or condoms) during the study and for 6 months after.
- You can complete online questionnaires at 1 month and 6 months after the procedure.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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