Clin2
NCT06996951Possibly a fitRecruiting

Sinus treatments in cystic fibrosis with modern modulator therapy

Cystic Fibrosis (CF)Chronic Rhinosinusitis (CRS)

Part of Digestive system, Genetic & congenital, Lungs & breathing clinical trials.

This study looks at how different sinus treatments affect people with cystic fibrosis who are taking modern modulator therapy. It aims to understand which rinses work best for chronic sinus problems.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
64 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 years or older
  • You must have cystic fibrosis and be taking a highly effective modulator therapy (like Trikafta)
  • You must have a history of chronic sinusitis
  • You must currently use nasal saline rinses (with or without added steroids or antibiotics)
  • You cannot be pregnant
  • You must not have had a sinus or nasal tumor, an active sinus or lung infection, or been hospitalized for a lung flare-up in the last 3 months, and you cannot have taken oral antibiotics for a sinus or lung infection in the last month

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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