Clin2
NCT07696338Possibly a fitNot yet recruiting

Studying fewer airway clearance treatments for children with cystic fibrosis

Cystic Fibrosis (CF)

Part of Digestive system, Genetic & congenital, Lungs & breathing clinical trials.

This study looks at whether doing airway clearance therapies less often can be just as effective as doing them every day for children and teens with cystic fibrosis who are taking a modulator medicine. The goal is to see if a simpler treatment schedule can keep lungs healthy while making daily life easier.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
405 people
Ages
3 years to 16 years
Study type
Interventional

Who can take part

  • Ages 3 to 16 years old (all genders)
  • A confirmed diagnosis of cystic fibrosis
  • Taking a CF medicine called a modulator (like Trikafta or a similar drug) for at least 3 months before the study starts and continuing it during the study
  • Lung function of at least 70% of what is expected for your age (checked with a breathing test)
  • Feeling stable - no major health changes or new treatments (such as antibiotics or steroids) in the 28 days before screening

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07148739Recruiting· Phase 4
Ensuring Best Access to CF Treatment

This study tests whether people with cystic fibrosis who are already on a triple combination CFTR modulator can stay on their treatment without interruptions or problems. It aims to make sure everyone gets the best, most consistent treatment for their CF.

Birmingham, Alabama
NCT06958094Not yet recruiting
Mobile app for airway clearance in cystic fibrosis

This study tests a fun mobile app designed to help children and teens with cystic fibrosis do their daily airway clearance exercises. If your child is between 8 and 20 years old and has CF, they might be able to join and possibly make breathing treatments more enjoyable.

Seville, Seville
NCT06654752Recruiting
Simpler treatment for lung flare-ups in kids with CF

This study tests a streamlined approach to managing sudden lung symptoms (pulmonary exacerbations) in children with cystic fibrosis. It aims to see if a simpler treatment plan works as well as standard care, which could mean less time in the hospital and fewer disruptions to daily life.

Birmingham, Alabama
NCT05248230Recruiting· Phase 2
Study drug for adults with cystic fibrosis lung disease

This Phase 2 trial tests 4D-710 to improve lung health in adults with cystic fibrosis who either cannot take CFTR modulator medicines or are not doing well enough on them. You may be eligible if you have moderate lung function and stable oxygen levels, and you meet other safety and health requirements.

Birmingham, Alabama
NCT06504589Recruiting
Study for CF treatments for people without modulators

This study tests new treatments for cystic fibrosis in people who cannot take or choose not to take current CFTR modulators. It aims to find better options for managing CF.

Birmingham, Alabama
NCT04509050Recruiting
Testing a highly effective CF medicine in young children

This study looks at how well a highly effective cystic fibrosis (CF) medicine works in infants and young children, and what biological changes it causes. It may help families understand whether the medicine improves CF function and related measures early in life.

Birmingham, Alabama

Hear when a new Cystic Fibrosis (CF) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.