New surgery vs. standard surgery for GERD
Part of Digestive system clinical trials.
This trial compares a new device called RefluxStop to a standard surgery (Nissen fundoplication) for treating long-term acid reflux. It aims to see which one works better at stopping heartburn and other symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have had acid reflux (GERD) for at least 12 months
- You are 18 or older
- You have a test showing acid in your esophagus for at least 4.5% of a 24-hour period (off acid-reducing meds for 7 days)
- You are healthy enough for general anesthesia and laparoscopic surgery
- You have not had any past weight-loss or anti-reflux surgery
- You are not pregnant or nursing
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial compares two surgical approaches (a 'partial wrap' and a 'full wrap' of the stomach around the esophagus) to fix a hiatal hernia and treat severe, hard-to-control reflux (GERD). It may be a good option if your reflux hasn't improved with medication and you have a hiatal hernia.
This study tests a new topical treatment for people with chronic heartburn and acid regurgitation who don't have erosions (damage) in their esophagus. The treatment is applied directly to the affected area and may help relieve symptoms without taking daily pills.
This registry study follows people with long-term acid reflux (GERD) who get the RefluxStop treatment. It mainly collects real-world safety and performance information to see how well the device helps over time.
This study will track how well the RefluxStop device works and its safety for treating acid reflux in a general hospital setting. It aims to help people with long-term GERD who have not found relief from other treatments.
This trial compares two surgical treatments for acid reflux (GERD) that isn't well controlled with medication. It tests if the LINX device (a magnetic ring around the esophagus) works as well or better than fundoplication (a stomach wrap). It may help people who need surgery for reflux.
This trial tests whether an endoscopic fundoplication procedure (a reflux surgery done through the scope) using the MUSE system can better control long-term reflux symptoms. It likely fits people with chronic reflux confirmed by testing who may be candidates for surgical treatment.
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