Clinical trials
GERD (Gastroesophageal Reflux Disease) clinical trials
Below are recruiting gerd (gastroesophageal reflux disease) clinical trials, each written for real people, not researchers. We’re tracking 44 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07749989Recruiting
Review of patients with gastroesophageal reflux disease
This study looks at patients who came to Beijing Friendship Hospital with stomach acid issues (GERD). Researchers want to understand how treatments like medications or anti-reflux surgery work over time. By joining, you help them improve care for others with the same condition.
Beijing, Beijing MunicipalityAges 18–90 - NCT07063576RecruitingPhase 2/Phase 3
Baclofen for persistent heartburn or regurgitation
This trial tests whether the drug baclofen can help patients who still have acid reflux symptoms (heartburn or regurgitation) despite taking standard treatments like PPIs for 8 weeks. If you've tried PPIs and still have symptoms, this may be an option.
DhakaAges 18 years+ - NCT07700342Recruiting
Could an evening gel improve sleep for nighttime reflux?
This trial tests a topical therapy you apply at night to see if it can improve sleep for people with non-erosive GERD who still have nighttime symptoms even while taking a morning acid reducer.
Warsaw, Masovian VoivodeshipAges 18 years+ - NCT04255693Recruiting
Real-life reflux study of diet and behavior changes
This study looks at how following specific diet and behavior changes affects symptoms of acid reflux (heartburn/regurgitation) in everyday life. It may help you understand what lifestyle steps improve reflux and how symptoms change over time.
MoscowAges 18–80 - NCT04506593Recruiting
GI Motility diagnosis registry for people with digestion movement problems
This trial is a registry, meaning it collects information about people being evaluated for problems with how the gut moves. It may help doctors better diagnose gastrointestinal motility disorders in the future.
Indianapolis, IndianaAges Any age - NCT05066594Recruiting
Registry for a procedure to treat long-term reflux
This is an observational study (no experimental treatment) that follows people who choose a specific procedure called transoral incisionless fundoplication (TIF) with the EsophyX device for long-term acid reflux. It aims to track outcomes for up to 5 years at San Raffaele Hospital.
MilanAges 18–80 - NCT05870163Recruiting
Registry study of RefluxStop for GERD patients
This registry study follows people with long-term acid reflux (GERD) who get the RefluxStop treatment. It mainly collects real-world safety and performance information to see how well the device helps over time.
FriedrichshafenAges 18 years+ - NCT06255886RecruitingPhase 4
Treatment for acid reflux in babies under 1 year
This trial tests a treatment for babies under 1 year old who have frequent and troublesome reflux (GERD). It aims to find a safe and effective way to reduce symptoms like crying, feeding problems, and breathing pauses.
Aabenraa, Region SyddanmarkAges 1 month–1 year - NCT07624383Recruiting
New topical treatment for nonerosive acid reflux disease
This study tests a new topical treatment for people with chronic heartburn and acid regurgitation who don't have erosions (damage) in their esophagus. The treatment is applied directly to the affected area and may help relieve symptoms without taking daily pills.
Warsaw, Masovian VoivodeshipAges 18 years+ - NCT06339801Recruiting
Mucosal impedance test for GERD diagnosis
This study tests a new way to measure how your esophagus lining reacts to acid (called mucosal impedance) to help diagnose GERD. It's for people who still have symptoms even after taking standard medication for 8 weeks.
Buenos AiresAges 18–65 - NCT06348420Recruiting
New procedure vs. acid-reducing pills for GERD
This study compares a new procedure called anti-reflux mucosal valvuloplasty (ARMV) to acid-reducing medicines (PPIs) for treating GERD. It may help people who have had reflux for a long time and need daily PPIs.
Jinan, ShandongAges 18–60 - NCT06495606Recruiting
How stomach acid affects your voice
This study looks at how stomach acid backing up into the throat can change the voice. It may help find typical voice differences in people with acid reflux.
BernAges 18 years+ - NCT06564246RecruitingPhase 4
Comparing Vonoprazan vs. Pantoprazole for GERD
This trial tests a newer medication called vonoprazan against the standard treatment pantoprazole for patients with gastroesophageal reflux disease (GERD). The goal is to see which one works better for controlling symptoms like heartburn and acid reflux over 8 weeks.
GizaAges 17–60 - NCT06564558Recruiting
Posture correction for GERD symptoms
This study tests whether teaching people with GERD to improve their posture can reduce their symptoms. It is for people with a rounded upper back (kyphosis) and a GERD diagnosis.
BeirutAges 18–60 - NCT06613438Recruiting
New wearable device for GERD symptoms
This study tests a new wearable device (eGERD) that aims to reduce symptoms of GERD (heartburn and regurgitation). The trial will check if the device is safe and works well without needing medication.
Chicago, IllinoisAges 22–75 - NCT06641375Recruiting
Heat treatment for chronic acid reflux (AREA study)
This trial tests a new way to treat GERD (chronic acid reflux) using a tiny camera and a device that delivers a gentle heat treatment (argon plasma coagulation) to the area where the stomach meets the esophagus. It's compared to a 'sham' procedure (you won't know which you get) to see if it stops acid from backing up better than medicine alone.
Hyderabad, TelanganaAges 18–70 - NCT06757296Recruiting
Endoscopic revision of sleeve gastrectomy for reflux or poor weight loss
This study tests a new, less invasive way to convert a sleeve gastrectomy into a different type of weight-loss surgery (SASI) in people who have ongoing gastroesophageal reflux or haven't lost enough weight. The goal is to see if this endoscopic procedure can improve reflux and help with weight loss without the need for a traditional surgery.
SingaporeAges 21–65 - NCT06928350Recruiting
Normal esophagus readings in healthy Indian adults
This trial is studying normal acid and fluid movement in the esophagus of healthy people in India. It will help doctors better understand what is typical, which may improve care for people with acid reflux or other swallowing issues.
Hyderabad, TelanganaAges 18–50 - NCT06984484Recruiting
Afluxin for GERD: safety and performance study
This trial tests a new treatment called Afluxin for people with gastroesophageal reflux disease (GERD), which causes heartburn and regurgitation. It aims to see if Afluxin is safe and works better than a placebo (inactive control) to relieve symptoms.
GenovaAges 18–75 - NCT06991348RecruitingPhase 4
Comparing two heartburn medicines: tegoprazan vs pantoprazole
This study tests whether a newer medicine, tegoprazan, works better than an older one, pantoprazole, for treating heartburn and acid reflux. Both are stomach acid reducers. You may be able to join if you have been diagnosed with GERD and your symptoms have lasted for at least three months.
Mexico City, Mexico CityAges 18 years+ - NCT07121803Recruiting
Special ice cream for esophagus health in diabetes
This study tests whether a special ice cream can help the esophagus (the tube that carries food to your stomach) work better in people with type 2 diabetes. Researchers want to see if the ice cream can improve how food moves down the esophagus.
MoscowAges 18–80 - NCT07125521Recruiting
Smartphone app study for GERD medication adherence
This study tests whether using a smartphone app called GERDCare helps people with GERD take their medications as prescribed. It may be a good fit if you have typical GERD symptoms like heartburn or regurgitation and are comfortable using a smartphone app.
HanoiAges 18 years+ - NCT07131397Recruiting
Breathing muscle training for GERD
This trial tests whether strengthening your breathing muscles can help reduce GERD symptoms. You may be eligible if you have GERD and are in generally good health without other major conditions.
Athens, AtticaAges 18–70 - NCT07252115Recruiting
Comparing two surgeries for hiatal hernia and stubborn GERD
This trial compares two surgical approaches (a 'partial wrap' and a 'full wrap' of the stomach around the esophagus) to fix a hiatal hernia and treat severe, hard-to-control reflux (GERD). It may be a good option if your reflux hasn't improved with medication and you have a hiatal hernia.
BeijingAges 18–85
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Common questions
- Are there clinical trials for gerd (gastroesophageal reflux disease)?
- Yes. Clin2 currently lists 44 recruiting gerd (gastroesophageal reflux disease) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gerd (gastroesophageal reflux disease) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gerd (gastroesophageal reflux disease) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.