LINX vs fundoplication for acid reflux surgery
Part of Digestive system clinical trials.
This trial compares two surgical treatments for acid reflux (GERD) that isn't well controlled with medication. It tests if the LINX device (a magnetic ring around the esophagus) works as well or better than fundoplication (a stomach wrap). It may help people who need surgery for reflux.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have acid reflux (GERD) that isn't well controlled with medication or you can't tolerate the medicine
- You have been diagnosed with GERD through tests like an endoscopy (camera down the throat) or a pH study (24-hour acid test)
- You either have no hiatal hernia or a small one (less than 5 cm/2 inches)
- Your esophagus has good muscle strength, shown by a manometry test (measures contractions)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial compares a new device called RefluxStop to a standard surgery (Nissen fundoplication) for treating long-term acid reflux. It aims to see which one works better at stopping heartburn and other symptoms.
This trial tests whether an endoscopic fundoplication procedure (a reflux surgery done through the scope) using the MUSE system can better control long-term reflux symptoms. It likely fits people with chronic reflux confirmed by testing who may be candidates for surgical treatment.
This trial tests a newer, less invasive surgical procedure called TIF (Transoral Incisional Fundoplication) for patients with severe acid reflux and regurgitation that hasn't improved with high-dose medications. The procedure is done through the mouth rather than the abdomen, and researchers will follow patients for 5 years to see if it works and is safe in Asian populations.
This trial tests a minimally invasive surgery to treat gastroesophageal reflux disease (GERD) in children. It aims to reduce symptoms and improve quality of life for kids who have not had prior reflux surgery.
This trial tests a procedure called Endoscopic Cardial Constriction Ligation (ECCL) to help people whose acid reflux doesn't improve with strong medication. It uses a thin, flexible tube with a camera to tighten the valve between the stomach and esophagus.
This trial studies an endoscopic procedure to treat gastroesophageal reflux disease (GERD) in people who had gastric sleeve surgery. It may help if reflux symptoms are not controlled on once-daily acid medicine (PPI) or if you cannot tolerate it and want an alternative.
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