Comparing two ways to give a sedative during nasal surgery
Part of Ear, nose & throat clinical trials.
This study compares two ways of giving a sedative called dexmedetomidine (one as a nose spray, one through an IV) to see which reduces the amount of pain medicine needed during nasal surgery. It aims to help patients have less pain and fewer side effects.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years old or older.
- You should be in generally good health (ASA I–II, meaning no serious conditions or only mild, well-controlled disease).
- You must be scheduled for nasal endoscopic surgery (surgery inside the nose using a small telescope) under general anesthesia.
- You must not have a heart rhythm problem like atrial fibrillation or a first-degree/second-degree heart block.
- You must not be allergic to dexmedetomidine.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests two inhaled medicines given before surgery to see which one works better for pain after nasal surgery. One medicine is ketamine and the other is dexmedetomidine, both given as a mist through a nebulizer.
This study compares two sedative medicines given as a nasal spray to help children relax and reduce separation anxiety before surgery. It aims to find which medicine works better for children aged 2 to 6.
This trial tests if a medicine called dexmedetomidine can help prevent agitation after nose surgery. You may be eligible if you are a healthy adult having planned nose surgery.
This trial tests a nasal spray that helps you feel calm and relaxed before anesthesia for your surgery. It may be an option for people having general anesthesia or other types of anesthesia, and the study checks if it is safe and works well.
This trial compares two safe, common ways to help children relax before surgery: a medicine sprayed in the nose versus a medicine given by mouth. The goal is to see which one works better and is easier for kids.
This trial tests if two different medicines, dexamethasone and dexmedetomidine, given as a nerve block in your nose during rhinoplasty can better control pain after surgery.
Hear when a new Functional Endoscopic Sinus Surgery (FESS) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.