Clin2
NCT07014137Possibly a fitRecruiting

A study of an oral pill for angiogenic sarcomas

Sarcoma

Part of Cancer clinical trials.

This trial tests an oral medication (ABSK043) that may help your immune system fight certain rare sarcomas. It is for people with intimal sarcoma, head and neck angiosarcoma, or epithelioid hemangioendothelioma that has spread or cannot be removed by surgery.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
20 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have one of these sarcoma types: intimal sarcoma, head and neck angiosarcoma, or epithelioid hemangioendothelioma (EHE).
  • Your cancer has spread or cannot be removed by surgery.
  • You are 18 years or older.
  • You can swallow and keep down oral medications.
  • You have not had prior treatment with a PD-1 or PD-L1 inhibitor.
  • You do not have active brain metastases or a history of pneumonitis or interstitial lung disease.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT04535713Recruiting· Phase 2
Testing chemotherapy plus immunotherapy for advanced sarcoma

This study tests a combination of chemo medicines (gemcitabine, doxorubicin, docetaxel) plus an immunotherapy drug (nivolumab) for advanced sarcoma that can’t be removed with surgery. It may help shrink tumors and slow disease growth in people whose cancer has already been treated and is measurable on scans.

Santa Monica, California
NCT03886311Recruiting· Phase 2
Talimogene, nivolumab, and trabectedin for advanced sarcoma

This Phase 2 study tests a combination treatment for locally advanced or metastatic sarcoma that cannot be fully removed by surgery. It aims to shrink tumors and control disease by combining an injected cancer-killing medicine with two cancer-fighting drugs.

Santa Monica, California
NCT03548428Recruiting· Phase 2
Targeted radiation for a small number of sarcoma metastases

This Phase 2 trial tests a highly focused radiation treatment to shrink sarcoma that has spread to a limited number of spots in the body. It may help control disease while limiting radiation to healthier tissue.

Bordeaux
NCT06074692Recruiting· Phase 2
PARP inhibitor, SBRT, and immunotherapy for advanced sarcoma

This trial tests a combination of a PARP inhibitor drug, targeted radiation (SBRT), and immunotherapy for people with advanced sarcoma that has spread. It aims to see if this triple therapy can shrink tumors or slow the disease.

Shanghai, Shanghai Municipality
NCT05961761Recruiting· Phase 2
Testing propranolol plus pembrolizumab for advanced sarcoma

This Phase 2 trial tests whether combining propranolol (a blood-pressure/heart medicine) with pembrolizumab (an immune therapy) can help people with advanced angiosarcoma or undifferentiated pleomorphic sarcoma that has progressed after first-line chemotherapy. It aims to slow tumor growth and improve outcomes while also studying tumor markers from your biopsy tissue.

Aarhus
NCT06699576Not yet recruiting· Phase 1
Testing a new drug combination for bone and soft tissue sarcoma

This trial tests a new drug called HS-20093 combined with other treatments for people with advanced bone or soft tissue sarcoma. It aims to find safe and effective combinations for those who haven't responded to standard treatments.

Hear when a new Sarcoma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.