Surfactant delivery methods for premature babies with breathing issues
Part of Lungs & breathing clinical trials.
This study compares two ways of giving surfactant (a natural substance that helps lungs stay open) to premature babies who need extra breathing support. It aims to find which method works better and is safer for infants born at 29 to 36 weeks.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Born at 29 to 36 weeks of pregnancy
- Weight at birth is 750 grams or more (about 1 pound 10 ounces)
- Currently receiving breathing support through a CPAP machine (a mask or prongs that help keep airways open)
- Needs extra oxygen (at least 25%) and qualifies for a procedure called LISA (less invasive surfactant administration)
- No need for a breathing tube before surfactant is given
- No severe birth defects, especially heart, airway, or brain problems
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares two methods—video laryngoscopy and direct laryngoscopy—to give surfactant (a medicine that helps babies' lungs work better) to very premature infants. It aims to find which method is safer and easier for babies born at 28 weeks or earlier who need surfactant within the first 36 hours after birth.
This study looks at different ways doctors give a life-saving medication called surfactant to premature babies who are struggling to breathe. Researchers want to understand which delivery methods work best and help improve care.
This trial tests if giving surfactant (a natural substance that helps lungs stay open) through a special airway device can help late preterm and early term infants with breathing problems. The goal is to see if this approach works better than current methods without needing a breathing tube.
This trial compares two types of surfactant (Calfactant and Poractant Alfa) given through a less invasive method to very premature babies with breathing problems. It aims to see if one works better at helping them breathe without needing a breathing tube.
This trial compares giving a breathing treatment (surfactant) over 1 minute versus 5 minutes to help very premature babies born before 28 weeks. The goal is to see which timing helps the baby's breathing and heart rate stabilize better.
This trial tests whether giving surfactant (a substance that helps lungs stay open) to premature babies with Respiratory Distress Syndrome (RDS) through a mask on the throat (supraglottic airway) is safe and effective. It may be an option for babies who need extra oxygen but are not on a breathing tube.
Hear when a new Surfactant trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.