Clin2
NCT07031570Possibly a fitNot yet recruiting

Liver treatment study for colorectal cancer spread

Colorectal Cancer Metastatic

Part of Cancer clinical trials.

This trial compares two ways to treat colorectal cancer that has spread to the liver and cannot be removed by surgery. It tests if combining a targeted chemo bead procedure (DEB-TACE) with liver chemo infusion (HAIC) works better than HAIC alone.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
500 people
Ages
18 years and older
Study type
Observational

Who can take part

  • You are 18 years or older.
  • You have colorectal cancer that has spread to the liver.
  • You have not had surgery to remove the liver tumors.
  • You have at least one measurable liver tumor on a scan from the last 31 days.
  • Your liver function is good enough (Child-Pugh class A or B).
  • You are able to carry out daily activities with minor help (ECOG 0-2).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06555003Recruiting· Phase 3
DEBIRI plus chemo vs. chemo alone for liver metastases

This trial tests if a treatment called DEBIRI (tiny beads delivering chemo directly to the liver) plus standard chemotherapy works better than chemotherapy alone for colorectal cancer that has spread to the liver and can't be fully removed by surgery.

Tehran, Tehran Province
NCT06563986Recruiting· Phase 2
Combination therapy for advanced colorectal cancer in the liver

This trial tests a combination of two chemotherapy drugs (FTD and tipiracil), a targeted therapy (bevacizumab), and a radiation treatment (radioembolization) for people with colorectal cancer that has spread mainly to the liver and hasn't responded to other treatments. The goal is to see if this combination can shrink tumors and help control the cancer.

Utrecht
NCT02885753Recruiting· Phase 3
Liver-only metastatic colon cancer trial using targeted chemo

This Phase 3 trial tests different ways to deliver chemotherapy for colon cancer that has spread only to the liver (with limited possible tiny lung spots). It looks at whether the treatment plan improves outcomes compared with another chemotherapy approach, using oxaliplatin and LV5FU2 (with or without irinotecan) plus an added targeted medicine.

Brussels
NCT06988852Recruiting· Phase 2
Chemo infusion into liver for colorectal cancer spread

This trial tests a strong chemotherapy combination given directly into the liver's blood supply (called HAIC) for people whose colorectal cancer has spread only to the liver and cannot be removed with surgery yet. The goal is to shrink the liver tumors enough so they can be surgically removed.

Wuhan, Hubei
NCT07570914Not yet recruiting· Phase 2
Chemotherapy after surgery for colorectal cancer with liver spread

This trial tests a combination of three chemotherapy drugs (liposomal irinotecan, oxaliplatin, and capecitabine) given directly into the liver blood vessel after surgery to remove colorectal cancer that has spread to the liver. The goal is to reduce the chance of cancer coming back.

NCT07117435Recruiting· Phase 1
Targeted chemo into liver for colorectal cancer spread

This trial is testing a new way to give the chemotherapy drug paclitaxel directly into the liver (through a tiny tube) along with standard systemic treatment for people whose colorectal cancer has spread only to the liver and cannot be surgically removed. The goal is to see if this targeted approach works better than standard treatment alone.

Lishui, Zhejiang

Hear when a new Colorectal Cancer Metastatic trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.