A study of an experimental drug for axial spondyloarthritis
Part of Bones, joints & muscles clinical trials.
This trial tests an investigational drug for people with axial spondyloarthritis (a type of inflammatory arthritis affecting the spine and pelvis). It also includes a group of healthy volunteers for comparison. The study aims to see if the drug is safe and effective.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old and have been diagnosed with axial spondyloarthritis (AxSpA).
- You have active inflammation visible on an MRI of the sacroiliac joints or a high level of C-reactive protein (CRP, a marker of inflammation in the blood).
- Your symptoms have lasted at least 3 months and started before age 40.
- You have moderate to high disease activity despite current treatment (score of 2.1 or higher on the ASDAS scale).
- You have had an inadequate response or intolerance to at least one NSAID (nonsteroidal anti-inflammatory drug).
- You have tried no more than one (or, if in Australia, no more than two) biologic or JAK inhibitor medications before this study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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