Study of a new drug for active ankylosing spondylitis
Part of Bones, joints & muscles clinical trials.
This study tests a new medication (called 608) for adults with active ankylosing spondylitis (AS). It aims to see if the drug can reduce AS symptoms and improve quality of life.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are at least 18 years old.
- You have been diagnosed with ankylosing spondylitis using the 1984 modified New York criteria.
- You have tried NSAIDs (like ibuprofen) and they didn't work well enough, or you can't take them.
- You are willing to use birth control and not plan pregnancy or donate sperm/eggs for at least 6 months after the last dose.
- You do not have other uncontrolled inflammatory diseases, active hepatitis B, C, or HIV, a history of cancer, or a weakened immune system.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new oral medication called LNK01001 for adults with active ankylosing spondylitis. It aims to reduce pain, stiffness, and inflammation when standard NSAID treatments no longer help.
This trial is for people with ankylosing spondylitis (a type of arthritis that affects the spine) who are otherwise healthy. It may test a treatment to see if it helps control symptoms, whether your disease is active or stable.
This study tests whether combining two types of immune-blocking drugs (an IL-17 inhibitor and a TNF inhibitor) works better than either alone for treating ankylosing spondylitis. It is for people whose symptoms are not well controlled with NSAIDs.
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This Phase 1 study tests how safe and tolerable an injection made from umbilical cord stem cells is for people with active ankylosing spondylitis. It may help doctors learn a new treatment approach and understand side effects in the short term.
This trial tests whether stem cells from umbilical cord can reduce pain and stiffness in people with ankylosing spondylitis (a disease causing spinal inflammation). You may qualify if you have active AS that hasn't responded well to standard treatments.
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