Study of atezolizumab with chemo and radiation for high-risk sarcoma
Treatments studied
Part of Cancer clinical trials.
This trial tests a combination of immunotherapy (atezolizumab), chemotherapy (doxorubicin), and radiation before and after surgery for people with high-risk soft tissue sarcoma in the arm, leg, or trunk. The goal is to see if this approach can improve outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 or older with a new or returning sarcoma in your arm, leg, or trunk that has not been treated before.
- Your tumor must be a specific type of sarcoma (like UPS, myxofibrosarcoma, or certain liposarcomas) and be grade 2 or 3.
- Your tumor must be larger than 5 cm on a recent scan and considered removable by surgery.
- You must be generally healthy enough for surgery and have adequate organ function (like blood counts and kidney/liver function).
- You cannot have had prior chemotherapy or radiation for this sarcoma, or have cancer that has spread to other parts of the body.
- You must agree to use effective birth control if you or your partner could become pregnant.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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