Root canal sealers and oxidative stress study
Part of Mouth & dental clinical trials.
This study is looking at how different types of root canal filling materials (sealers) affect oxidative stress markers in the body. It is for people with a single tooth that has a chronic infection at the root tip and needs a root canal.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be generally healthy (ASA 1) and between 18 and 45 years old.
- You must have one tooth with at least two roots that has a chronic root tip infection (lesion smaller than 2 cm).
- Your infected tooth must be non-vital (nerve is dead), confirmed by cold and electric tests.
- You must have completed initial gum disease treatment (phase 1 periodontal treatment).
- You must not smoke, drink alcohol, or have used antibiotics in the last 3 months or pain relievers in the last 2 weeks.
- You cannot be pregnant, obese, have active gum disease, or have had head and neck radiation.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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